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Gene Expression Data
Assay Details
Assay
Reference: J:67151 Kruger M, et al., Sonic hedgehog is a survival factor for hypaxial muscles during mouse development. Development. 2001 Mar;128(5):743-52
Assay type: RNA in situ
MGI Accession ID: MGI:2149560
Gene symbol: Myod1
Gene name: myogenic differentiation 1
Probe: MyoD probe9
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 2A Present in the muscle precursors.

Specimen 2D: embryonic day 10.5; ShhDsh/ShhDsh (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted 2D Expression was present in the muscle precursors, but it was slightly delayed relative to wild type.

Specimen not shown: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Structure Level Pattern Image Note
TS17: forelimb bud mesenchyme Present Regionally restricted Expression was present in the muscle precursors, but it was slightly delayed relative to wild type.

Specimen 2G: embryonic day 10.5 (more )
Note: This specimen was stained as a whole mount, embedded in gelatin, and cut on a vibratome.
Structure Level Pattern Image Note
TS17: trunk dermomyotome Present Regionally restricted 2G Present in the hypaxial and epaxial domains.
TS17: forelimb bud mesenchyme Present Regionally restricted 2G Present in the muscle precursors.

Specimen 2J: embryonic day 10.5; ShhDsh/ShhDsh (more )
Note: This specimen was stained as a whole mount, embedded in gelatin, and cut on a vibratome.
Structure Level Pattern Image Note
TS17: trunk dermomyotome Strong Regionally restricted 2J Expression was present in the hypaxial domain but absent from the epaxial domain.
TS17: forelimb bud mesenchyme Present Regionally restricted 2J Expression was present in the muscle precursors, but it was slightly delayed relative to wild type.

Specimen not shown: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Note: This specimen was stained as a whole mount, embedded in gelatin, and cut on a vibratome.
Structure Level Pattern Image Note
TS17: trunk dermomyotome Strong Regionally restricted Expression was present in the hypaxial domain but absent from the epaxial domain.
TS17: forelimb bud mesenchyme Present Regionally restricted Expression was present in the muscle precursors, but it was slightly delayed relative to wild type.

Specimen 3F: embryonic day 10.5; ShhDsh/ShhDsh (more )
Note: The somites of mutant embryos display significant malformations. In the dorsomedial region next to the neural tube, no epithelium was discernible. This specimen was embedded in gelatin and cut on a vibratome.
Structure Level Pattern Image Note
TS17: trunk dermomyotome Present Regionally restricted 3F Expression was present in the hypaxial domain but absent from the epaxial domain.

Specimen not shown: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Note: The somites of mutant embryos display significant malformations. In the dorsomedial region next to the neural tube, no epithelium was discernible. This specimen was embedded in gelatin and cut on a vibratome.
Structure Level Pattern Image Note
TS17: trunk dermomyotome Present Regionally restricted Expression was present in the hypaxial domain but absent from the epaxial domain.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory