Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Utrntm1Ked
Name:	utrophin; targeted mutation 1, Kay E Davies
MGI ID:	MGI:2148589
Synonyms:	Utr-
Gene:	Utrn  Location: Chr10:12257932-12745109 bp, - strand  Genetic Position: Chr10, 3.77 cM
Alliance:	Utrntm1Ked page

Germline Transmission:	Earliest citation of germline transmission: J:70949
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion   Mutation details: Insertion of a neomycin cassette into exon 7. No protein was detected in extracts derived from kidney, lung or brain of homozygous mice as assayed by Western blot analysis. (J:70949)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 9 strains available      Cell Lines: 0 lines available
Carrying any Utrn Mutation:	306 strains or lines available

Original:	J:70949 Deconinck AE, et al., Postsynaptic abnormalities at the neuromuscular junctions of utrophin-deficient mice. J Cell Biol. 1997 Feb 24;136(4):883-94
All:	71 reference(s)