Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ctnnb1tm2.1Kem
Name:	catenin beta 1; targeted mutation 2.1 Rolf Kemler
MGI ID:	MGI:2148569
Synonyms:	beta-catenindel, Ctnnb1Del, floxdel
Gene:	Ctnnb1  Location: Chr9:120762466-120789573 bp, + strand  Genetic Position: Chr9, 72.19 cM
Alliance:	Ctnnb1tm2.1Kem page

Germline Transmission:	Earliest citation of germline transmission: J:67966
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Intragenic deletion   Mutation details: This allele is a derivative of Catnbtm2Kem in which Cre mediated recombination removed exons 2 through 6. (J:67966)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	182 assay results 3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	34 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ctnnb1 Mutation:	49 strains or lines available

Original:	J:67966 Brault V, et al., Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development. 2001 Apr;128(8):1253-64
All:	54 reference(s)