Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Hectd1opm
Name:	HECT domain E3 ubiquitin protein ligase 1; open mind
MGI ID:	MGI:2137552
Synonyms:	opm
Gene:	Hectd1  Location: Chr12:51790505-51876319 bp, - strand  Genetic Position: Chr12, 22.11 cM
Alliance:	Hectd1opm page

Strain of Origin:

C57BL/6J

Allele Type:    Chemically induced (ENU) (Null/knockout) Mutation:    Single point mutation   Mutation details: An ENU-induced T-to-A mutation changes leucine codon 144 to a premature stop codon (total peptide length is 2611 amino acids). The resulting truncated protein, which is probably not expressed, lacks an ankyrin repeat, a mib domain and a terminal HECT domain. (J:122594) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	30 assay results
In Structures Affected by this Mutation:	9 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hectd1 Mutation:	141 strains or lines available

Original:	J:48268 Kasarskis A, et al., A phenotype-based screen for embryonic lethal mutations in the mouse. Proc Natl Acad Sci U S A. 1998 Jun 23;95(13):7485-90
All:	8 reference(s)