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Gene Expression Data
Assay Details
Assay
Reference: J:29332 Baldwin HS, et al., Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development. Development. 1994 Sep;120(9):2539-53
Assay type: Immunohistochemistry
MGI Accession ID: MGI:2136892
Gene symbol: Pecam1
Gene name: platelet/endothelial cell adhesion molecule 1
Antibody: mAb 390
Detection system: Secondary antibody coupled to fluorescein
Results
Specimen 7A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: endocardial tube Present 7A Expression in the endocardial cells of the developing heart.
TS13: extraembryonic component Present 7A Expression in the extra-embryonic mesoderm of the yolk sac corresponding to the region of blood island formation.
TS13: dorsal aorta Present 7A
TS13: cardiac muscle tissue Absent 7A

Specimen 7B: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: endocardial tube Present Regionally restricted 7B Expression within the developing endothelium.
TS13: dorsal aorta Present Regionally restricted 7B Expression within the developing endothelium, a single layer of cells surrounding the lumen of the dorsal aorta.
TS13: extraembryonic component Present Regionally restricted 7B Expression in the extra-embryonic mesoderm of the yolk sac corresponding to the region of blood island formation.

Specimen 7C, D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: endocardial lining Strong 7C , 7D
TS19: endocardial cushion Strong Regionally restricted 7C , 7D Expression on the endothelium of the endocardial cushions of the outflow tract.
TS19: outflow tract Strong Regionally restricted 7C , 7D Expression on the endothelium of the endocardial cushions of the outflow tract.

Specimen 8B: embryonic day 8.0 (more )
Structure Level Pattern Image Note
TS12: blood island Present Regionally restricted 8B , 8D Staining is restricted to the the endothelial lining of blood islands within the yolk sac mesoderm.
TS12: yolk sac Present Regionally restricted 8B , 8D Staining is restricted to the the endothelial lining of blood islands within the yolk sac mesoderm.
TS12: yolk sac endoderm Absent 8B , 8D


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory