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Gene Expression Data
Assay Details
Assay
Reference: J:40605 Miyamoto N, et al., Defects of urogenital development in mice lacking Emx2. Development. 1997 May;124(9):1653-64
Assay type: RNA in situ
MGI Accession ID: MGI:2136467
Gene symbol: Emx2
Gene name: empty spiracles homeobox 2
Probe: Emx2 probe1
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 4A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: nephrogenic cord Present 4A Authors report that staining is detected in the presumptive nephrogenic cord.

Specimen 4B: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: nephric duct Present 4B Staining is detected in the Wolffian duct.

Specimen 4C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: nephric duct Present 4C Expression in the Wolffian duct, mesonephric tubules and coelomic epithelium.
TS17: mesonephric tubule Present 4C Expression in the Wolffian duct, mesonephric tubules and coelomic epithelium.
TS17: peritoneal component Present 4C Expression in the Wolffian duct, mesonephric tubules and coelomic epithelium.
TS17: mesonephros mesenchyme Absent 4C

Specimen 4D: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: nephric duct Present 4D Expression in the Wolffian duct, mesonephric tubules and coelomic epithelium.
TS19: mesonephric tubule Present 4D Expression in the Wolffian duct, mesonephric tubules and coelomic epithelium.
TS19: peritoneal component Present 4D Expression in the Wolffian duct, mesonephric tubules and coelomic epithelium.
TS19: mesonephros mesenchyme Absent 4D No expression in surrounding mesenchyme cells, including pretubular cell aggregates.

Specimen 4E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: ureteric bud Present 4E
TS19: metanephric mesenchyme Absent 4E

Specimen 4F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: nephric duct Present 4F Expression in the Wolffian duct, mesonephric tubules and gonad.
TS20: mesonephric tubule Present 4F Expression in the Wolffian duct, mesonephric tubules and gonad.
TS20: gonad Present 4F Expression in the Wolffian duct, mesonephric tubules and gonad.
TS20: reproductive system Present Regionally restricted 4F Authors report expression in the Mullerian (paramesonephric) duct.

Specimen 4G: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: ureter Present 4G Expression in the branched ureter
TS20: mesenchyme of metanephros Present Regionally restricted 4G Expression in "a unique population of" mesenchyme cells, which are undergoing epithelialization.

Specimen 4H: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: nephric duct Present 4H Expression in the Wolffian duct, Mullerian duct and branched ureter.
TS21: paramesonephric duct of female Present 4H Expression in the Wolffian duct, Mullerian duct and branched ureter.
TS21: ureter Present 4H Expression in the Wolffian duct, Mullerian duct and branched ureter.
TS21: mesonephros Present Regionally restricted 4H Expression in the mesonephric tubules and gonad.
TS21: reproductive system Present Regionally restricted 4H Expression in the mesonephric tubules and gonad.
TS21: metanephros Present Regionally restricted 4H Expression in mesenchyme cells which are undergoing epithelialization; more restricted than those in cells at a later stage of epithelialization.

Specimen 4I: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: renal cortex Present 4I Expression restricted to the cortical zone where new nephric tubules are being formed.
TS24: collecting duct Present Regionally restricted 4I Decreased expression in collecting ducts of the medial zone.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory