About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:21942 Feijen A, et al., Expression of activin subunits, activin receptors and follistatin in postimplantation mouse embryos suggests specific developmental functions for different activins. Development. 1994 Dec;120(12):3621-37
Assay type: RNA in situ
MGI Accession ID: MGI:2135923
Gene symbol: Acvr2b
Gene name: activin receptor IIB
Probe: Acvr2b cDNA1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen decidua: postnatal (more )
Note: At early postimplantation stages.
Structure Level Pattern Image Note
TS28: decidua Absent

Specimen 6.0-day p.c.: embryonic day 6.0 (more )
Structure Level Pattern Image Note
TS8: embryo Strong At 6.0 to 8.5 dpc.
TS8: extraembryonic component Strong At 6.0 to 8.5 dpc.

Specimen 8.5-day p.c.: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: embryo Strong At 6.0 to 8.5 dpc.
TS13: extraembryonic component Strong At 6.0 to 8.5 dpc.

Specimen 10E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: central nervous system Present Regionally restricted 10E Predominantly present in the central nervous system, including the brain, ganglia and spinal cord.
TS20: embryo Present Regionally restricted 10E Predominantly present in the central nervous system, including the brain, ganglia and spinal cord.
TS20: brain Present Regionally restricted 10E Expressed in the mantle layer; also in the ependymal layer.
TS20: spinal cord Present Regionally restricted 10E Expressed in the mantle layer; also in the ependymal layer.
TS20: diencephalon Present 10E
TS20: telencephalon Present 10E
TS20: metanephros Present Regionally restricted 10E Peripheral structures in the metanephros.
TS20: eye Present Regionally restricted 10E Epidermis of the developing eye.
TS20: stomach Present Regionally restricted 10E Epithelium and mesenchymal layers of the stomach.

Specimen 10F: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: central nervous system Present Regionally restricted 10F Predominantly present in the central nervous system, including the brain, ganglia and spinal cord.
TS20: embryo Present Regionally restricted 10F Predominantly present in the central nervous system, including the brain, ganglia and spinal cord.
TS20: brain Present Regionally restricted 10F Expressed in the mantle layer; also in the ependymal layer.
TS20: spinal cord Present Regionally restricted 10F Expressed in the mantle layer; also in the ependymal layer.
TS20: cochlear duct epithelium Present 10F
TS20: diencephalon Present 10F
TS20: posterior semicircular canal Present 10F
TS20: superior semicircular canal Present 10F
TS20: telencephalon Present 10F

Specimen 10G: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: brain Present Regionally restricted 10G Expressed in the mantle layer; also in the ependymal layer.
TS20: spinal cord Present Regionally restricted 10G Expressed in the mantle layer; also in the ependymal layer.
TS20: metanephros Present Regionally restricted 10G Peripheral structures in the metanephros.

Specimen Table 1: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS21: olfactory lobe Present Regionally restricted Expression is restricted to the epithelium.
TS21: cochlear duct epithelium Present
TS21: vibrissa Absent
TS21: eye Present Regionally restricted Epidermis of the developing eye.
TS21: tooth Absent
TS21: tongue mesenchyme Present Developing muscles of the tongue.
TS21: genital tubercle Absent
TS21: lung Ambiguous Either positive or negative.
TS21: stomach Ambiguous Either positive or negative.
TS21: esophagus Absent
TS21: liver Absent
TS21: rectum Absent
TS21: trachea Absent
TS21: metanephros Present Regionally restricted Peripheral structures in the metanephros.
TS21: brain Present Expressed in the mantle layer; also in the ependymal layer.
TS21: spinal cord Present Expressed in the mantle layer; also in the ependymal layer.
TS21: intestine Present
TS21: vertebral axis musculature Absent There is no expression in the body wall.
TS21: blood vessel Absent
TS21: heart Absent
TS21: axial skeleton Absent There is no expression in the intervertebral discs.
TS21: gonad Ambiguous Either positive or negative; may be due to sex differences.
TS21: pleuro-peritoneal canal Absent There is no expression in the pleuroperitoneal membrane.
TS21: trunk mesenchyme Present Regionally restricted There is expression in the fascia. In addition expression is in mesenchymal condensations of the flank and back of the embryo, in particular in the limb and shoulder regions.
TS21: limb Present
TS21: shoulder Present

Specimen 10H: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS21: neural retinal epithelium Present 10H


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory