Acvr2a RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:21942 Feijen A, et al., Expression of activin subunits, activin receptors and follistatin in postimplantation mouse embryos suggests specific developmental functions for different activins. Development. 1994 Dec;120(12):3621-37
Assay type:	RNA in situ
MGI Accession ID:	MGI:2135922
Gene symbol:	Acvr2a
Gene name:	activin receptor IIA

Probe:	Acvr2a cDNA1
Probe preparation:	Antisense labelled with S35 RNA
Visualized with:	Autoradiography

Results

Specimen decidua: postnatal (more

)
Note: At early postimplantation stages.

Structure	Level	Pattern	Image	Note
TS28: decidua	Absent

Specimen 6.0-day p.c.: embryonic day 6.0 (more

)

Structure	Level	Pattern	Image	Note
TS8: embryo	Absent			From 6.0 to 8.5 dpc.
TS8: extraembryonic component	Absent			From 6.0 to 8.5 dpc.

Specimen 8.5-day p.c.: embryonic day 8.5 (more

)

Structure	Level	Pattern	Image	Note
TS13: embryo	Absent			From 6.0 to 8.5 dpc.
TS13: extraembryonic component	Absent			From 6.0 to 8.5 dpc.

Specimen 9.5-day p.c.: embryonic day 9.5 (more

)

Structure	Level	Pattern	Image	Note
TS15: embryo	Present

10A ©

Specimen 10A: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: central nervous system	Present	Regionally restricted	10A	Predominantly expressed in the central nervous system, including the brain, ganglia and spinal cord.
TS20: embryo	Present	Regionally restricted	10A	Predominantly expressed in the central nervous system, including the brain, ganglia and spinal cord.
TS20: central nervous system ganglion	Present		10A
TS20: perioptic mesenchyme	Present	Regionally restricted	10A	Fascia of developing ocular muscles.
TS20: cochlear duct epithelium	Present		10A
TS20: posterior semicircular canal	Present		10A
TS20: superior semicircular canal	Present		10A
TS20: stomach	Weak	Regionally restricted	10A	Epithelium and mesenchymal layers.

10B ©

Specimen 10B: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: central nervous system	Present	Regionally restricted	10B	Predominantly expressed in the central nervous system, including the brain, ganglia and spinal cord.
TS20: embryo	Present	Regionally restricted	10B	Predominantly expressed in the central nervous system, including the brain, ganglia and spinal cord.
TS20: brain	Present	Regionally restricted	10B	Selectively expressed in the mantle layer.
TS20: corpus striatum	Present	Regionally restricted	10B	Selectively expressed in the mantle layer.
TS20: diencephalon lateral wall mantle layer	Present		10B
TS20: spinal cord mantle layer	Present		10B

10C ©

Specimen 10C: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS20: central nervous system	Present	Regionally restricted	10C	Predominantly expressed in the central nervous system, including the brain, ganglia and spinal cord.
TS20: embryo	Present	Regionally restricted	10C	Predominantly expressed in the central nervous system, including the brain, ganglia and spinal cord.
TS20: brain	Present	Regionally restricted	10C	Selectively expressed in the mantle layer.
TS20: corpus striatum	Present	Regionally restricted	10C	Selectively expressed in the mantle layer.
TS20: tongue	Present	Regionally restricted	10C	Mesenchyme of the tongue.
TS20: occipital myotome	Present	Regionally restricted	10C	Developing muscles of the tongue.

10D ©

Specimen 10D: embryonic day 12.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: vibrissa	Present	Regionally restricted	10D
TS21: eye	Present	Regionally restricted	10D	Epidermis of the developing eye.

Specimen Table 1, 12.5-day p.c.: embryonic day 12.5 (more

)

Structure	Level	Pattern	Note
TS21: olfactory lobe	Present	Regionally restricted	Expression is restricted to the epithelium.
TS21: cochlear duct epithelium	Present
TS21: vibrissa	Present	Regionally restricted	Expression is restricted to the epithelium.
TS21: eye	Present	Regionally restricted	Epidermis of the developing eye and fascia of developing ocular muscles.
TS21: tooth	Absent
TS21: tongue mesenchyme	Present		Developing muscles of the tongue.
TS21: genital tubercle	Absent
TS21: lung	Ambiguous		Either positive or negative, possibly by sex difference.
TS21: stomach	Ambiguous		Either positive or negative, possibly by sex difference.
TS21: esophagus	Absent
TS21: liver	Absent
TS21: metanephros	Absent
TS21: rectum	Absent
TS21: trachea	Absent
TS21: brain mantle layer	Present		Expression is present in the mantle layer.
TS21: corpus striatum	Present		Expression is present in the mantle layer.
TS21: brain	Present
TS21: intestine	Present
TS21: spinal cord	Present
TS21: vertebral axis musculature	Absent		There is no expression in the body wall.
TS21: blood vessel	Absent
TS21: heart	Absent
TS21: axial skeleton	Absent		There is no expression in the intervertebral discs.
TS21: gonad	Absent
TS21: pleuro-peritoneal canal	Absent		There is no expression in the pleuroperitonal membrane.
TS21: trunk mesenchyme	Present	Regionally restricted	Expression is present in the fascia. Also in mesenchymal condensations of the flank and back of the embryo, in particular in the limb and shoulder regions.
TS21: limb	Present
TS21: shoulder	Present

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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