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Amnamn
Transgenic Allele Detail
Summary
Symbol: Amnamn
Name: amnionless
MGI ID: MGI:2135304
Synonyms: amn, Tg(CD8A)T81-3Ehl
Gene: Amn  Location: Chr12:111237530-111242860 bp, + strand  Genetic Position: Chr12, 60.94 cM
Alliance: Amnamn page
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic
Mutation:    Insertion
 
Mutation detailsIntegration of three to five copies of the human CD8A transgene into the Amn gene caused a small deletion at the insertion site. Heterozygote mutant mice express low levels of human CD8A mRNA in spleen, thymus, and brain. (J:68615)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Amn Mutation:  19 strains or lines available
Notes
At one time amn was thought to be an allele of Traf3 J:34163.
References
Original:  J:34163 Wang X, et al., A candidate gene for the amnionless gastrulation stage mouse mutation encodes a TRAF-related protein. Dev Biol. 1996 Jul 10;177(1):274-90
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory