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Gene Expression Data
Assay Details
Assay
Reference: J:66343 Gaunt SJ, et al., Mouse homeo-genes within a subfamily, Hox-1.4, -2.6 and -5.1, display similar anteroposterior domains of expression in the embryo, but show stage- and tissue-dependent differences in their regulation. Development. 1989 Sep;107(1):131-41
Assay type: RNA in situ
MGI Accession ID: MGI:1934226
Gene symbol: Hoxb4
Gene name: homeobox B4
Probe: Hox-2.6 cDNA1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1 C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: central nervous system Present Regionally restricted 1C
TS20: spinal cord Present 1C Trancripts were most concentrated in dorsal parts of the spinal cord.

Specimen 2 B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: central nervous system Present Regionally restricted 2B
TS20: medulla oblongata Present Regionally restricted 2B The anterior boundary was found in the mid-myelencephalon.

Specimen 3 B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: C1 vertebral cartilage condensation Weak 3B Weak labeling especially in ventral parts.
TS20: C2 vertebral cartilage condensation Strong 3B
TS20: vertebral cartilage condensation Present Graded 3B A gradual anterior to posterior decline (Fig. 1C and 3B).
TS20: lumbar vertebral cartilage condensation Present Graded 3B A very slight increase in the abundance of transcripts in the lumbar region.
TS20: lung Present Regionally restricted 3B Transcripts were found in the mesodermal derivatives but not the lining endothelium of the lung.

Specimen 5 C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: thymus primordium Present 5C
TS20: thyroid gland Present 5C
TS20: trachea Present Regionally restricted 5C Expression in the mesodermal derivatives (not lining endothelium) of the trachea.
TS20: pharynx Present Regionally restricted 5C Expression in the floor of the pharynx posterior and anterior to the thyroid duct but absent in posterior parts of the pharyngeal floor.
TS20: tongue Absent 5C No expression over the tongue.

Specimen 6 C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: stomach Present Regionally restricted 6C Transcripts were abundant in the mesodermal derivatives and in the mesentery underlying the stomach.
TS20: liver Absent 6C
TS20: mesonephros Present 6C
TS20: metanephros Present 6C Expression was observed in a neighboring section.
TS20: testis Absent 6C
TS20: stomach epithelium Absent 6C No expression in the lining endothelium of the stomach.

Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: gut Present Regionally restricted Expression in posterior regions of the intestine.

Specimen 7 C: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: lateral plate mesoderm Present Regionally restricted 7C Transcripts were confined to more posterior parts, lateral plate mesoderm, somtatic mesoderm, and neurectoderm.
TS13: neural ectoderm Present Regionally restricted 7C Transcripts were confined to more posterior parts, lateral plate mesoderm, somtatic mesoderm, and neurectoderm.
TS13: trunk paraxial mesenchyme Present Regionally restricted 7C Transcripts were confined to more posterior parts, lateral plate mesoderm, somtatic mesoderm, and neurectoderm.

Specimen 8 C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future spinal cord Present 8C Expression in lateral plate mesoderm, somatic mesoderm, and neurectoderm.
TS15: trunk mesenchyme Present 8C Expression in lateral plate mesoderm, somatic mesoderm, and neurectoderm.
TS15: trunk paraxial mesenchyme Present 8C Expression in lateral plate mesoderm, somatic mesoderm, and neurectoderm.

Specimen 9 C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: lung Present Regionally restricted 9A/C Abundant expression in the mesodermal components of the lung.

Specimen 9 D: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: stomach Present Regionally restricted 9B/D Abundant expression in the mesodermal components of the stomach.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory