Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Ntf3tm1Par
Name:	neurotrophin 3; targeted mutation 1, Luis F Parada
MGI ID:	MGI:1933844
Synonyms:	NT-3-, NT-3BRP, NT-3neo
Gene:	Ntf3  Location: Chr6:126078375-126143703 bp, - strand  Genetic Position: Chr6, 60.45 cM
Alliance:	Ntf3tm1Par page

Germline Transmission:	Earliest citation of germline transmission: J:67562
Parent Cell Line:	CJ7 (ES Cell)
Strain of Origin:	129S1/Sv-Oca2+ Tyr+ Kitl+

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion     A neomycin cassette was inserted into the only coding exon, disrupting gene function. (J:67562, J:97779)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	17 assay results
In Structures Affected by this Mutation:	42 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ntf3 Mutation:	24 strains or lines available

Original:	J:67562 Tessarollo L, et al., Targeted mutation in the neurotrophin-3 gene results in loss of muscle sensory neurons. Proc Natl Acad Sci U S A. 1994 Dec 6;91(25):11844-8
All:	16 reference(s)