Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Msx1tm1Bero
Name:	msh homeobox 1; targeted mutation 1, Benoit Robert
MGI ID:	MGI:1933766
Synonyms:	Msx1-, Msx1nlacZ, Msx1-nlacZ
Gene:	Msx1  Location: Chr5:37977835-37981929 bp, - strand  Genetic Position: Chr5, 20.21 cM
Alliance:	Msx1tm1Bero page

Germline Transmission:	Earliest citation of germline transmission: J:42035
Parent Cell Line:	HM-1 (ES Cell)
Strain of Origin:	129P2/OlaHsd-Hprt1b-m3

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: An n-lacZ reporter gene was inserted in-frame into the sequence encoding the third helix of the homeodomain. A fusion protein of the first 43 amino acids and beta-galactosidase is expressed from this allele. (J:42035)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	282 assay results
In Structures Affected by this Mutation:	19 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Msx1 Mutation:	18 strains or lines available

Original:	J:42035 Houzelstein D, et al., Insertional mutation of the mouse Msx1 homeobox gene by an nlacZ reporter gene. Mech Dev. 1997 Jul;65(1-2):123-33
All:	28 reference(s)