Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Brca2tm1Mak
Name:	breast cancer 2, early onset; targeted mutation 1, Tak W Mak
MGI ID:	MGI:1930617
Synonyms:	Brca210-11
Gene:	Brca2  Location: Chr5:150446095-150493794 bp, + strand  Genetic Position: Chr5, 89.52 cM
Alliance:	Brca2tm1Mak page

Germline Transmission:	Earliest citation of germline transmission: J:40595
Parent Cell Line:	E14K (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion     Replacement of the 3' half of exon 10, intron 10 and the 5'end of exon 11 with a neomycin cassette. (J:40595)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Brca2 Mutation:	132 strains or lines available

Original:	J:40595 Suzuki A, et al., Brca2 is required for embryonic cellular proliferation in the mouse. Genes Dev. 1997 May 15;11(10):1242-52
All:	3 reference(s)