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Gene Expression Data
Assay Details
Assay
Reference: J:49912 Bei M, et al., FGFs and BMP4 induce both Msx1-independent and Msx1-dependent signaling pathways in early tooth development. Development. 1998 Nov;125(21):4325-33
Assay type: RNA in situ
MGI Accession ID: MGI:1929939
Gene symbol: Dlx2
Gene name: distal-less homeobox 2
Probe: Dlx2 cDNA5
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Assay notes: Probe was reduced to an average size of 100-150bp by hydrolysis.
Results
Specimen 3 C: embryonic day 11.5 (more )
Note: Dental lamina stage of tooth development.
Structure Level Pattern Image Note
TS19: mandibular process Present Regionally restricted 3C Expression in dental mesenchyme.
TS19: maxillary process Present Regionally restricted 3C Expression in dental mesenchyme.
Specimen 3 D: embryonic day 11.5; Msx1tm1Rilm/Msx1tm1Rilm (more )
Note: Dental lamina stage of tooth development.
Structure Level Pattern Image Note
TS19: mandibular process Present Regionally restricted 3D Expression in dental mesenchyme.
TS19: maxillary process Present Regionally restricted 3D Expression in dental mesenchyme.
Specimen 3 G: embryonic day 13.0 (more )
Note: Tooth bud stage.
Structure Level Pattern Image Note
TS21: lower jaw molar mesenchyme Present 3G
TS21: upper jaw molar mesenchyme Present 3G
Specimen 3 H: embryonic day 13.0; Msx1tm1Rilm/Msx1tm1Rilm (more )
Note: Tooth bud stage.
Structure Level Pattern Image Note
TS21: lower jaw molar mesenchyme Present 3H Reduced expression relative to wild-type.
TS21: upper jaw molar mesenchyme Present 3H Reduced expression relative to wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory