Summary | Mutation origin | Mutation description | Expression | Phenotypes | Tumor data | Find Mice (IMSR) | References

Symbol:	Cdkn2dtm1Maro
Name:	cyclin dependent kinase inhibitor 2D; targeted mutation 1, Martine F Roussel
MGI ID:	MGI:1927668
Synonyms:	INK4d-
Gene:	Cdkn2d  Location: Chr9:21199759-21202553 bp, - strand  Genetic Position: Chr9, 7.76 cM
Alliance:	Cdkn2dtm1Maro page

Germline Transmission:	Earliest citation of germline transmission: J:58959
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion     Insertion of a LacZ-neomycin fusion gene (beta-geo) into the second exon of the INK4d gene. (J:58959) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

List all tumor models in MMHCdb carrying Cdkn2dtm1Maro

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Cdkn2d Mutation:	25 strains or lines available

Original:	J:58959 Zindy F, et al., INK4d-deficient mice are fertile despite testicular atrophy. Mol Cell Biol. 2000 Jan;20(1):372-8
All:	16 reference(s)