Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Ntn1Gt(ST629)Byg
Name:	netrin 1; gene trap ST629, BayGenomics
MGI ID:	MGI:1927548
Synonyms:	Netrin-1-, Netrin-1betageo, Netrin-1LacZ, ntn1 -, Ntn1Gt, Ntn1Gt(pGT1.8TM)629Ecs, Ntn1Gt(pGT1.8TM)629Wcs
Gene:	Ntn1  Location: Chr11:68100190-68277652 bp, - strand  Genetic Position: Chr11, 41.45 cM, cytoband B3
Alliance:	Ntn1Gt(ST629)Byg page

Mutant Cell Line:	ST629
Germline Transmission:	Earliest citation of germline transmission: J:37125
Parent Cell Line:	E14 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Gene trapped (Null/knockout, Reporter) Mutation:    Insertion of gene trap vector     Vector: pGT1.8TM   Mutation details: The integration of gene trap vector pGT1.8TM occurred in an intron of the netrin 1 gene. The mutant allele is likely to be hypomorphic rather than null, since some of the wild-type transcripts are present, presumably by splicing over the inserted sequences. (J:37125) Inheritance:    Recessive Sequence Tags:  Sequence tag details (1 tag) Tag ID GenBank ID Method Tag Location (trapped strand)* Select ST629 CC144759 (MGI Seq Detail) 5' RACE Chr11:68168248-68168399 bp (-) * GRCm39 (strand of gene trap mutagenesis) Selected Tags: download BLAST at NCBI Genome Context:  Genome Browser view of this mutation 26 gene trap insertions have trapped this gene View all gene trap sequence tags in this region

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	129 assay results
In Structures Affected by this Mutation:	7 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Ntn1 Mutation:	106 strains or lines available

Original:	J:37125 Serafini T, et al., Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system. Cell. 1996 Dec 13;87(6):1001-14
All:	81 reference(s)