Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	Nrgntm1Kph
Name:	neurogranin; targeted mutation 1, Kuo-Ping Huang
MGI ID:	MGI:1927195
Synonyms:	Ng-
Gene:	Nrgn  Location: Chr9:37455789-37464041 bp, - strand  Genetic Position: Chr9, 20.78 cM
Alliance:	Nrgntm1Kph page

Germline Transmission:	Earliest citation of germline transmission: J:65166
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129/Sv

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: Insertion of a LacZ gene in frame into the first coding exon, followed by a neomycin cassette. No NRGN immunoreactivity was detected in brain sections derived from homozygous mutant mice. X-gal staining in homozygous mutant mice corresponded with the NRGN positive staining in wild-type mice. (J:65166)

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nrgn Mutation:	5 strains or lines available

Original:	J:65166 Pak JH, et al., Involvement of neurogranin in the modulation of calcium/calmodulin-dependent protein kinase II, synaptic plasticity, and spatial learning: A study with knockout mice. Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11232-7
All:	12 reference(s)