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Gene Expression Data
Assay Details
Assay
Reference: J:24115 Shawlot W, et al., Requirement for Lim1 in head-organizer function [see comments]. Nature. 1995 Mar 30;374(6521):425-30
Assay type: RNA in situ
MGI Accession ID: MGI:1926827
Gene symbol: Egr2
Gene name: early growth response 2
Probe: Krox20 probe11
Probe preparation: Antisense labelled with digoxigenin RNA
Assay notes: Wild-type specimens were either homozygous wild-type or heterozygous mutant.
Results
Specimen 4e: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: rhombomere 3 Present 4e Expression in a region corresponding to rhombomeres 3 and 5.
TS15: rhombomere 5 Present 4e Expression in a region corresponding to rhombomeres 3 and 5.

Specimen 4f: embryonic day 9.5; Lhx1tm1Bhr/Lhx1tm1Bhr (more )
Structure Level Pattern Image Note
TS15: rhombomere 3 Present 4f The size of the expression domain in rhombomere 3 appears smaller as compared to wild type.
TS15: rhombomere 5 Present 4f
TS15: migrating neural crest Present 4f Expression in neural crest cells migrating from rhombomere 5.
TS15: spinal ganglion Present 4f

Specimen 6a top panel: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: rhombomere 3 Present 6a wt
TS13: rhombomere 5 Present 6a wt

Specimen 6a bottom panel: embryonic day 8.5; Lhx1tm1Bhr/Lhx1tm1Bhr (more )
Structure Level Pattern Image Note
TS13: rhombomere 3 Present Regionally restricted 6a -/- Two rhombomere-5 domains of expression are present on each side of the embryo and an enlarged rhombomere-3-staining region is also evident.
TS13: rhombomere 5 Present Regionally restricted 6a -/- Two rhombomere-5 domains of expression are present on each side of the embryo and an enlarged rhombomere-3-staining region is also evident.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/30/2025
MGI 6.24
The Jackson Laboratory