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Tg(KRT5-cre)1Tak
Transgene Detail
Summary
Symbol: Tg(KRT5-cre)1Tak
Name: transgene insertion 1, Junji Takeda
MGI ID: MGI:1926815
Synonyms: K5Cre, (K5)-Cre, K5-Cre, Keratin5Cre, Tg(Cre)1Tak
Transgene: Tg(KRT5-cre)1Tak  Location: unknown  
Alliance: Tg(KRT5-cre)1Tak page
Transgene
origin
Strain of Origin:  (C57BL/6 x C3H)F2
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(KRT5-cre)1Tak expression driven by 1 gene
 
Mutation detailsA 14kb fragment of human keratin 5 (KRT5) promoter was used to control the expression of Cre in keratinocytes. A nuclear localization signal was added to the 5' end of the Cre gene. (J:41746)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: KRT5 (human)
Summary of all recombinase alleles driven by KRT5.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 22 assay results
3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 7 anatomical structure(s)
Tumor Data
List all tumor models in MMHCdb carrying Tg(KRT5-cre)1Tak
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:41746 Tarutani M, et al., Tissue-specific knockout of the mouse Pig-a gene reveals important roles for GPI-anchored proteins in skin development. Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7400-5
All:  135 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory