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Gene Expression Data
Assay Details
Assay
Reference: J:60975 Chang H, et al., Smad5 is essential for left-right asymmetry in mice. Dev Biol. 2000 Mar 1;219(1):71-8
Assay type: RNA in situ
MGI Accession ID: MGI:1891684
Gene symbol: Lefty1
Gene name: left right determination factor 1
Results
Specimen 2A: embryonic day 8.0 (more )
Note: 1-2 somites. frontal view
Structure Level Pattern Image Note
TS12: future hindbrain floor plate Weak Regionally restricted 2A Expression is detected on the left side of the putative floor plate.
TS12: future midbrain floor plate Weak Regionally restricted 2A Expression is detected on the left side of the putative floor plate.
TS12: future prosencephalon floor plate Weak Regionally restricted 2A Expression is detected on the left side of the putative floor plate.
TS12: neural tube floor plate Weak Regionally restricted 2A Expression is detected on the left side of the putative floor plate.
TS12: lateral plate mesoderm Present Regionally restricted 2A Expression is detected on the left side of the lateral plate mesoderm.

Specimen 2B: embryonic day 8.0 (more )
Note: 1-2 somites. lateral view
Structure Level Pattern Image Note
TS12: future hindbrain floor plate Weak Regionally restricted 2B Expression is detected on the left side of the putative floor plate.
TS12: future midbrain floor plate Weak Regionally restricted 2B Expression is detected on the left side of the putative floor plate.
TS12: future prosencephalon floor plate Weak Regionally restricted 2B Expression is detected on the left side of the putative floor plate.
TS12: neural tube floor plate Weak Regionally restricted 2B Expression is detected on the left side of the putative floor plate.
TS12: lateral plate mesoderm Present Regionally restricted 2B Expression is detected on the left side of the lateral plate mesoderm.

Specimen 2C: embryonic day 8.0; Smad5tm1Zuk/Smad5tm1Zuk (more )
Note: 1-2 somites. frontal view
Structure Level Pattern Image Note
TS12: embryo Absent 2C

Specimen 2D: embryonic day 8.0; Smad5tm1Zuk/Smad5tm1Zuk (more )
Note: 1-2 somites. lateral view
Structure Level Pattern Image Note
TS12: embryo Absent 2D

Specimen Table 1: embryonic day 8.0; Smad5tm1Zuk/Smad5tm1Zuk (more )
Note: 3-4 somites.
Structure Level Pattern Image Note
TS12: lateral plate mesoderm Absent This was the expression pattern in 3 of 3 cases.
TS12: future hindbrain floor plate Present Regionally restricted Expression detected on the left side of the putative floor plate. This was the expression pattern in 1 of 3 cases.
TS12: future midbrain floor plate Present Regionally restricted Expression detected on the left side of the putative floor plate. This was the expression pattern in 1 of 3 cases.
TS12: future prosencephalon floor plate Present Regionally restricted Expression detected on the left side of the putative floor plate. This was the expression pattern in 1 of 3 cases.
TS12: neural tube floor plate Present Regionally restricted Expression detected on the left side of the putative floor plate. This was the expression pattern in 1 of 3 cases.

Specimen Table 1: embryonic day 8.0; Smad5tm1Zuk/Smad5tm1Zuk (more )
Note: 3-4 somites.
Structure Level Pattern Image Note
TS12: future hindbrain floor plate Absent This was the expression pattern in 2 of 3 cases.
TS12: future midbrain floor plate Absent This was the expression pattern in 2 of 3 cases.
TS12: future prosencephalon floor plate Absent This was the expression pattern in 2 of 3 cases.
TS12: neural tube floor plate Absent This was the expression pattern in 2 of 3 cases.
TS12: lateral plate mesoderm Absent This was the expression pattern in 3 of 3 cases.

Specimen Table 1: embryonic day 8.0; Smad5tm1Zuk/Smad5tm1Zuk (more )
Note: 3-4 somites.
Structure Level Pattern Image Note
TS12: future hindbrain floor plate Absent This was the expression pattern in 5 of 5 cases.
TS12: future midbrain floor plate Absent This was the expression pattern in 5 of 5 cases.
TS12: future prosencephalon floor plate Absent This was the expression pattern in 5 of 5 cases.
TS12: lateral plate mesoderm Absent This was the expression pattern in 5 of 5 cases.
TS12: neural tube floor plate Absent This was the expression pattern in 5 of 5 cases.

Specimen Table 1: embryonic day 8.5; Smad5tm1Zuk/Smad5tm1Zuk (more )
Note: 7-8 somites.
Structure Level Pattern Image Note
TS13: future hindbrain floor plate Absent This was the expression pattern in 6 of 6 cases.
TS13: future midbrain floor plate Absent This was the expression pattern in 6 of 6 cases.
TS13: future prosencephalon floor plate Absent This was the expression pattern in 6 of 6 cases.
TS13: lateral plate mesoderm Absent This was the expression pattern in 6 of 6 cases.
TS13: neural tube floor plate Absent This was the expression pattern in 6 of 6 cases.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory