Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Gsdma3Rim3
Name:	gasdermin A3; recombination induced mutation 3
MGI ID:	MGI:1861663
Gene:	Gsdma3  Location: Chr11:98517186-98529052 bp, + strand  Genetic Position: Chr11, 62.21 cM
Alliance:	Gsdma3Rim3 page

Strain of Origin:

H2wm7 x B10.MOL-SGR x B10.H2

Allele Type:    Spontaneous Mutation:    Single point mutation   Mutation details: A single base c.1042>A substitution results in an alanine to threonine amino acid residue change at position 348 (p.A348T). Introduction into wild-type mice of BAC clones engineered to carry this mutation results in an identical phenotype to that of mice with this allele. (J:122738) Inheritance:    Dominant

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

8 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gsdma3 Mutation:	26 strains or lines available

Original:	J:3639 Shiroishi T, et al., III. Mammalian genetics. Mouse visible mutations of the intra-MHC recombinants. Annu Rep Natl Inst Genet Jpn. 1992;42:49
All:	3 reference(s)