Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Lhx1tm1Bhr
Name:	LIM homeobox protein 1; targeted mutation 1, Richard R Behringer
MGI ID:	MGI:1857848
Synonyms:	Lim-, Lim1-, Limdelta
Gene:	Lhx1  Location: Chr11:84409110-84416361 bp, - strand  Genetic Position: Chr11, 51.31 cM
Alliance:	Lhx1tm1Bhr page

Germline Transmission:	Earliest citation of germline transmission: J:24115
Parent Cell Line:	AB1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A genomic fragment containing the entire coding region of the gene was replaced with a neomycin selection cassette. (J:24115)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	146 assay results
In Structures Affected by this Mutation:	16 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Lhx1 Mutation:	22 strains or lines available

Original:	J:24115 Shawlot W, et al., Requirement for Lim1 in head-organizer function [see comments]. Nature. 1995 Mar 30;374(6521):425-30
All:	21 reference(s)