Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Itga3tm1Jak
Name:	integrin alpha 3; targeted mutation 1, Jordan A Kreidberg
MGI ID:	MGI:1857792
Synonyms:	alpha3-, alpha3beta1-deficient, alpha 3 beta 1 integrin-deficient
Gene:	Itga3  Location: Chr11:94935300-94967627 bp, - strand  Genetic Position: Chr11, 59.01 cM
Alliance:	Itga3tm1Jak page

Germline Transmission:	Earliest citation of germline transmission: J:36831
Parent Cell Line:	J1 (ES Cell)
Strain of Origin:	129S4/SvJae

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion     A neomycin resistance cassette was inserted into the site that corresponds to cDNA nucleotide 1065. (J:36831)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	33 assay results
In Structures Affected by this Mutation:	8 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Itga3 Mutation:	52 strains or lines available

Original:	J:36831 Kreidberg JA, et al., Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesis. Development. 1996 Nov;122(11):3537-47
All:	29 reference(s)