Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Dlx5tm1Jlr
Name:	distal-less homeobox 5; targeted mutation 1, John L Rubenstein
MGI ID:	MGI:1857789
Synonyms:	Dlx5-, Dlx5tm1Ucsf
Gene:	Dlx5  Location: Chr6:6877801-6882068 bp, - strand  Genetic Position: Chr6, 2.83 cM
Alliance:	Dlx5tm1Jlr page

Germline Transmission:	Earliest citation of germline transmission: J:56559
Parent Cell Line:	JM-1 (ES Cell)
Strain of Origin:	129X1/SvJ

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A PGK-neomycin resistance cassette replaced 2.2kb of sequence including exons 1 and 2. The mutant allele is predicted to express a truncated protein that lacks the N-terminus, which includes 43 amino acids of the homeodomain. (J:56559)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	59 assay results 3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	56 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Dlx5 Mutation:	23 strains or lines available

Original:	J:56559 Depew MJ, et al., Dlx5 regulates regional development of the branchial arches and sensory capsules. Development. 1999 Sep;126(17):3831-46
All:	10 reference(s)