Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Mesp1tm1Ysa
Name:	mesoderm posterior 1; targeted mutation 1, Yumiko Saga
MGI ID:	MGI:1857785
Synonyms:	Mesp1-beta-gal, Mesp1lacZ
Gene:	Mesp1  Location: Chr7:79441989-79443338 bp, - strand  Genetic Position: Chr7, 45.16 cM
Alliance:	Mesp1tm1Ysa page

Germline Transmission:	Earliest citation of germline transmission: J:55840
Parent Cell Line:	TT2 (ES Cell)
Strain of Origin:	(C57BL/6NCrlj x CBA/JNCrlj)F1

Allele Type:    Targeted (Null/knockout, Reporter) Mutation:    Insertion   Mutation details: A lacZ reporter gene and pgk-neo cassette were ligated in frame at a NcoI site located at the translational initiation site of the gene, creating a knock-in vector that initiated lacZ translation at the same initiation site as the coding sequence of the gene. (J:55840)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	101 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mesp1 Mutation:	17 strains or lines available

Original:	J:55840 Saga Y, et al., MesP1 is expressed in the heart precursor cells and required for the formation of a single heart tube. Development. 1999 Aug;126(15):3437-47
All:	1 reference(s)