Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Adcy1tm1Drs
Name:	adenylate cyclase 1; targeted mutation 1, Daniel R Storm
MGI ID:	MGI:1857775
Synonyms:	AC1-, I-AC-
Gene:	Adcy1  Location: Chr11:7013489-7128506 bp, + strand  Genetic Position: Chr11, 4.72 cM, cytoband A2
Alliance:	Adcy1tm1Drs page

Germline Transmission:	Earliest citation of germline transmission: J:22287
Parent Cell Line:	AB1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1+

Allele Type:    Targeted (Null/knockout) Mutations:    Insertion, Intragenic deletion   Mutation details: A neomycin selection casssette replaced a genomic fragment including part of exon 1. Northern blot analysis demonstrated that the transcript was not detectable in RNA from homozygous mice. (J:22287)

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

12 assay results 1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Adcy1 Mutation:	70 strains or lines available

Original:	J:22287 Wu ZL, et al., Altered behavior and long-term potentiation in type I adenylyl cyclase mutant mice. Proc Natl Acad Sci U S A. 1995 Jan 3;92(1):220-4
All:	55 reference(s)