Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Hoxd13spdh
Name:	homeobox D13; synpolydactyly homolog
MGI ID:	MGI:1857397
Gene:	Hoxd13  Location: Chr2:74498654-74501943 bp, + strand  Genetic Position: Chr2, 44.13 cM
Alliance:	Hoxd13spdh page

Strain of Origin:

B6C3Fe a/a-Csf1op/J

Allele Type:    Spontaneous Mutation:    Insertion   Mutation details: 21 bp in-frame duplication within a polyalanine-encoding region at the 5'-end of the Hoxd13 coding sequence. This duplication expands the stretch of alanines from 15 to 22, the same type of expansion that occurs in human synpolydactyly mutations. (J:47974) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	152 assay results
In Structures Affected by this Mutation:	11 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Hoxd13 Mutation:	24 strains or lines available

Original:	J:47974 Johnson KR, et al., A new spontaneous mouse mutation of Hoxd13 with a polyalanine expansion and phenotype similar to human synpolydactyly. Hum Mol Genet. 1998 Jun;7(6):1033-8
All:	7 reference(s)