Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Lipctm1Unc
Name:	lipase, hepatic; targeted mutation 1, University of North Carolina
MGI ID:	MGI:1857182
Synonyms:	hl-, HL-deficient
Gene:	Lipc  Location: Chr9:70705410-70859503 bp, - strand  Genetic Position: Chr9, 39.57 cM
Alliance:	Lipctm1Unc page

Germline Transmission:	Earliest citation of germline transmission: J:22938
Parent Cell Line:	E14TG2a (ES Cell)
Strain of Origin:	129P2/OlaHsd

Allele Type:    Targeted (Null/knockout) Mutation:    Insertion     A neomycin resistance cassette was inserted into exon 4 of the gene. (J:22938)

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Lipc Mutation:	37 strains or lines available

Original:	J:22938 Homanics GE, et al., Mild dyslipidemia in mice following targeted inactivation of the hepatic lipase gene. J Biol Chem. 1995 Feb 17;270(7):2974-80
All:	34 reference(s)