Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | Notes | References

Symbol: Muc19sld Name: mucin 19; sublingual gland differentiation arrest MGI ID: MGI:1857043 Gene: Muc19  Location: Chr15:91722531-91832440 bp, + strand  Genetic Position: Chr15, 46.14 cM, cytoband E3 Alliance: Muc19sld page

Sublingual gland abnormalities in Muc19tm2Culp/Muc19tm2Culp, and Muc19sld/Muc19sld adults Show the 1 phenotype image(s) involving this allele.

Strain of Origin:

NFS/N

Allele Type:    Spontaneous (Null/knockout) Mutation:    Insertion   Mutation details: A spontaneous mutation inserted two CA repeats in intron 53 that results in decreased transcript stability. Additional mutations include: insertion of two GA repeats within intron 18, insertion of two T residues within intron 57 and a putative site within intron 52 of an TA repeat region that was intractable to sequencing. RT-PCR confirmed the absence of transcript expression in the sublingual gland. Inheritance:    Recessive

Schematic of the spontaneous Muc19sld mutation

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

1 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Muc19 Mutation:	41 strains or lines available

Original:	J:25317 Kojima A, New mutant: Sublingual gland differentiation arrest in the NFS/N subline. Mouse News Lett. 1988;80:147
All:	19 reference(s)