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th45
Spontaneous Allele Detail
Summary
Symbol: th45
Name: t-complex; t, Harwell 45
MGI ID: MGI:1856741
Gene: t  Location: unknown  Genetic Position: Chr17, Syntenic
Alliance: th45 page
Mutation
origin
Mutation
description
Allele Type:    Spontaneous
Mutation:    Other
 
Mutation detailsThis t-haplotype allele arose by homologous recombination between DNA markers T119I and T66E in wild-type and t6 haplotype chromatin. th45 carries t DNA that extends over Tcp-1 and includes the t-specific form of RP17. This represents recombination between wild-type and t haplotype chromosomes across the proximal inversion. (J:8163, J:20080)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any t Mutation:  19 strains or lines available
References
Original:  J:7443 Lyon MF, Transmission ratio distortion in mouse t-haplotypes is due to multiple distorter genes acting on a responder locus. Cell. 1984 Jun;37(2):621-8
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory