Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Symbol:	tw5G
Name:	t-complex; t, wild 5G
MGI ID:	MGI:1856718
Gene:	t  Location: unknown  Genetic Position: Chr17, Syntenic
Alliance:	tw5G page

Strain of Origin:

wild-derived

Allele Type:    Spontaneous Mutation:    Nucleotide repeat expansion   Mutation details: This t haplotype includes a mutation in Vps52, Vps52t-w5+Art that inserts a third G nucleotide, in addition to the 2 inserted in Vps52t-w5, at the start of exon 2 in a stretch of consecutive G nucleotides (9 in the wild-type C57BL/6 sequence, 11 in Vps52t-w5). The insertion of an additional G nucleotide restores the reading frame of Vps52 back to the wild-type frame. (J:190873) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any t Mutation:	19 strains or lines available

Original:	J:8713 Uehara H, et al., The molecular organization of the H-2K region of two t-haplotypes: implications for the evolution of genetic diversity. EMBO J. 1987 Jan;6(1):83-90
All:	4 reference(s)