Summary | Mutation origin | Mutation description | Expression | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol: Rpl24Bst Name: ribosomal protein L24; belly spot and tail MGI ID: MGI:1856685 Synonyms: Bst Gene: Rpl24  Location: Chr16:55786638-55791798 bp, + strand  Genetic Position: Chr16, 33.74 cM, cytoband C1 Alliance: Rpl24Bst page

Rpl24Bst/Rpl24+ and control Show the 3 phenotype image(s) involving this allele.

Strain of Origin:

C57BLKS/J

Allele Type:    Spontaneous (Hypomorph) Mutation:    Intragenic deletion   Mutation details: A 4 bp deletion disrupts the first intron branchpoint and causes abnormal splicing with retention of intron 1. The deletion removes a critical adenosine that reacts to form the lariat intermediate. PCR indicated that this is a hypomorphic allele where heterozygotes have approximately 60% of normal transcript levels and homozygotes have 20%. (J:92052) Inheritance:    Semidominant

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	127 assay results
In Structures Affected by this Mutation:	20 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rpl24 Mutation:	24 strains or lines available

Original:	J:13703 Southard JL, et al., Bst. Mouse News Lett. 1977;56:40
All:	26 reference(s)