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Mafbkr
Radiation induced Allele Detail
Summary
Symbol: Mafbkr
Name: MAF bZIP transcription factor B; kreisler
MGI ID: MGI:1856419
Synonyms: Krmlkr, MafbKrml-kr
Gene: Mafb  Location: Chr2:160205623-160208985 bp, - strand  Genetic Position: Chr2, 80.92 cM
Alliance: Mafbkr page
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Radiation induced
Mutation:    Inversion
 
Mutation detailsThere is a chromosomal inversion approximately 0.8 +/- 0.8cM in length very near the Mafb gene. The protein product of the normal gene is a transcription factor. The effect of the inversion appears to be to abolish transcription from the Mafb gene, not by physical disruption of the transcribed sequence, but by separation of coding sequences from a putative regulatory element or introduction of an inhibitory element. (J:4596, J:22020, J:83936)
Inheritance:    Recessive
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 167 assay results
In Structures Affected by this Mutation: 13 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Mafb Mutation:  18 strains or lines available
References
Original:  J:208 Hertwig P, Neue Mutationen und Koppelungsgruppen bei der Hausmaus. Z Indukt Abstamm Vererbungsl. 1942;80(1):220-246
All:  19 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory