Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	KitW-55J
Name:	KIT proto-oncogene receptor tyrosine kinase; dominant spotting 55 Jackson
MGI ID:	MGI:1856251
Gene:	Kit  Location: Chr5:75735647-75817382 bp, + strand  Genetic Position: Chr5, 39.55 cM
Alliance:	KitW-55J page

Strain of Origin:

C57BL/6J

Allele Type:    Spontaneous Mutation:    Single point mutation   Mutation details: Nucleotide sequence analysis revealed that a C-to-T point mutation results in the substitution of threonine with methionine at position 660 (p.T660M), which is within the ATP-binding domain. (J:28221) Inheritance:    Semidominant

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

2 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Kit Mutation:	179 strains or lines available

Original:	J:16313 Sweet HO, Remutations at The Jackson Laboratory. Mouse Genome. 1993;91(4):862-65
All:	3 reference(s)