Mitf<mi-rw> Spontaneous Allele Detail MGI Mouse (MGI:1856091)

Mitf^mi-rw
Spontaneous Allele Detail

Summary

Symbol:	Mitf^mi-rw
Name:	melanogenesis associated transcription factor; red eyed white
MGI ID:	MGI:1856091
Gene:	Mitf Location: Chr6:97784013-97998310 bp, + strand Genetic Position: Chr6, 45.05 cM
Alliance:	Mitf^mi-rw page

Mutation
origin

Strain of Origin:

CBA/J

Mutation
description

Allele Type:		Spontaneous
Mutation:		Intragenic deletion
		Mutation details: This allele contains a large genomic deletion that begins approximately 6kb upstream of the melanocyte-specific 5' end and includes the heart-specific 5'end encompassing exons 1H,1D and 1B. (J:21366, J:132153)
Inheritance:		Recessive

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 3 strains available Cell Lines: 0 lines available
Carrying any Mitf Mutation:	72 strains or lines available

Notes

Mitf^mi-rw/Mitf^mi mice are all white with small or absent eyes; Mitf^mi-rw/Mitf^mi-sp, fully pigmented except for a white belly spot; and Mitf^mi-rw/Mitf^Mi-wh mostly white with tan spots and red eyes (J:13661).

References

Original:	J:13661 Southard JL, Red-eyed white (mi^rw). Mouse News Lett. 1974;51:23
All:	6 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23