Summary | Mutation origin | Mutation description | Expression | Phenotypes | Find Mice (IMSR) | References

Symbol:	Lystbg-2J
Name:	lysosomal trafficking regulator; beige 2 Jackson
MGI ID:	MGI:1855970
Gene:	Lyst  Location: Chr13:13764982-13953388 bp, + strand  Genetic Position: Chr13, 5.28 cM
Alliance:	Lystbg-2J page

Strain of Origin:

Yellow stock

Allele Type:    Spontaneous Mutation:    Insertion   Mutation details: This allele was identified by a noncomplementation test with Lystbg. Quantitative reverse transcription showed the molecular fault in the Lystbg-2J mutation may be an intronic retrotransposition event causing a five-fold decrease in transcription and mRNA instability. (J:34205) Inheritance:    Recessive

View phenotypes and curated references for all genotypes (concatenated display).

In Structures Affected by this Mutation:

3 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Lyst Mutation:	225 strains or lines available

Original:	J:65327 Lane PW, bg-beige and bg2J - beige-2J. Mouse News Lett. 1962;26:35
All:	5 reference(s)