About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:58081 Lettice L, et al., The dominant hemimelia mutation uncouples epithelial-mesenchymal interactions and disrupts anterior mesenchyme formation in mouse hindlimbs. Development. 1999 Nov;126(21):4729-36
Assay type: RNA in situ
MGI Accession ID: MGI:1347627
Gene symbol: Fgf4
Gene name: fibroblast growth factor 4
Probe: Fgf4 probe11
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindlimb bud apical ectodermal ridge Present Regionally restricted 2A Expression is limited to the posterior two-thirds.

Specimen 2B: embryonic day 10.5; Dh/Dh+ (more )
Structure Level Pattern Image Note
TS17: hindlimb bud apical ectodermal ridge Present Regionally restricted 2B Expression has shifted to the anterior when compared to wild-type.

Specimen 2C: embryonic day 10.5; Dh/Dh (more )
Structure Level Pattern Image Note
TS17: hindlimb bud apical ectodermal ridge Present Regionally restricted 2C Expression has shifted anteriorly when compared to wild-type

Specimen 2G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Present Regionally restricted 2G Expression is restricted to the posterior two thirds.

Specimen 2H: embryonic day 11.5; Dh/Dh+ (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Present Regionally restricted 2H There is no posterior expression in the mutant. Expression is at the anterior extreme.

Specimen 2I: embryonic day 11.5; Dh/Dh (more )
Structure Level Pattern Image Note
TS19: footplate apical ectodermal ridge Present Regionally restricted 2I There is no posterior expression in the mutant. Expression is at the anterior extreme.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
01/28/2026
MGI 6.24
The Jackson Laboratory