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Gene Expression Data
Assay Details
Assay
Reference: J:41540 Rossel M, et al., Mice mutant for both Hoxa1 and Hoxb1 show extensive remodeling of the hindbrain and defects in craniofacial development. Development. 1999 Nov;126(22):5027-40
Assay type: Immunohistochemistry
MGI Accession ID: MGI:1346705
Gene symbol: Hoxb1
Gene name: homeobox B1
Antibody: anti-Hoxb1 rabbit
Detection system: Secondary antibody coupled to Texas Red
Results
Specimen 7A: embryonic day 8.5; Hoxa1tm1Mrc/Hoxa1+, Hoxb1tm3Mrc/Hoxb1+ (more )
Note: Double labeled: red - Hoxb1; green - Egr2 (assay MGI:1346699).
Structure Level Pattern Image Note
TS13: rhombomere 4 Present 7A
Specimen 7B: embryonic day 8.5; Hoxa1tm1Mrc/Hoxa1tm1Mrc (more )
Note: Double labeled: red - Hoxb1; green - Egr2 (assay MGI:1346699).
Structure Level Pattern Image Note
TS13: future hindbrain Present Regionally restricted 7B Relative to morphological markers such as the preotic and otic sulci and the position of the first somite, the anterior boundary of expression is at a more posterior level than in control embryos.
Specimen 7C: embryonic day 8.5; Hoxa1tm1Mrc/Hoxa1tm1Mrc, Hoxb1tm3Mrc/Hoxb1+ (more )
Note: Double labeled: red - Hoxb1; green - Egr2 (assay MGI:1346699).
Structure Level Pattern Image Note
TS13: future hindbrain Present 7C The anterior boundary of expression is at a more posterior level than in control embryos and aaBB embryos.
Specimen 7D: embryonic day 10.0; Hoxa1tm1Mrc/Hoxa1+, Hoxb1tm3Mrc/Hoxb1+ (more )
Note: Double labeled: red - Hoxb1; green - Egr2 (assay MGI:1346699).
Structure Level Pattern Image Note
TS16: rhombomere 4 Strong 7D
TS16: tail neural crest Present Regionally restricted 7D Neural crest cells emanating from rhombomere 4 express Hoxb1.
Specimen 7E: embryonic day 10.0; Hoxa1tm1Mrc/Hoxa1tm1Mrc, Hoxb1tm3Mrc/Hoxb1+ (more )
Note: Double labeled: red - Hoxb1; green - Egr2 (assay MGI:1346699).
Structure Level Pattern Image Note
TS16: future hindbrain Present Single cells 7E Only a vestige of cells in the neural tube express Hoxb1.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory