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Gene Expression Data
Assay Details
Assay
Reference: J:41540 Rossel M, et al., Mice mutant for both Hoxa1 and Hoxb1 show extensive remodeling of the hindbrain and defects in craniofacial development. Development. 1999 Nov;126(22):5027-40
Assay type: Immunohistochemistry
MGI Accession ID: MGI:1346703
Gene symbol: Crabp1
Gene name: cellular retinoic acid binding protein I
Antibody: anti-CRABP I
Detection system: Secondary antibody coupled to fluorescein
Assay notes: There are two Crabp1 antibodies. Either antibody may have been used in this assay. See MGI:4460229 for details about the second antibody.
Results
Specimen 5I: embryonic day 9.0; Hoxa1tm1Mrc/Hoxa1+, Hoxb1tm3Mrc/Hoxb1+ (more )
Structure Level Pattern Image Note
TS14: migrating neural crest Present Regionally restricted 5I CRABPI is present in three major neural crest cell populations emanating from r2, r4 and r6 migrating into the 3 branchial arches.
Specimen 5J: embryonic day 9.0; Hoxa1tm1Mrc/Hoxa1tm1Mrc, Hoxb1tm3Mrc/Hoxb1+ (more )
Structure Level Pattern Image Note
TS14: migrating neural crest Present Regionally restricted 5J Only two populations of migratory neural crest are labeled, one at the r2/r3 level and the second caudal to the otocyst, migrating into the 1st and 3rd arch, respectively.
Specimen 5K: embryonic day 9.0; Hoxa1tm1Mrc/Hoxa1tm1Mrc, Hoxb1tm3Mrc/Hoxb1tm3Mrc (more )
Structure Level Pattern Image Note
TS14: migrating neural crest Present Regionally restricted 5K Only two populations of migratory neural crest are labeled, migrating into the 1st and 3rd arch.
Specimen 5L: embryonic day 9.0; Hoxa1tm1Mrc/Hoxa1tm1Mrc, Hoxb1tm3Mrc/Hoxb1tm3Mrc (more )
Structure Level Pattern Image Note
TS14: migrating neural crest Present Regionally restricted 5L Only two populations of migratory neural crest are labeled, migrating into the 1st and 3rd arch.
Specimen 8F +/-;+/-: embryonic day 9.5; Hoxa1tm1Mrc/Hoxa1+, Hoxb1tm3Mrc/Hoxb1+ (more )
Note: 20-25 somites. Double labeled: green - Crabp1; red - TUNEL.
Structure Level Pattern Image Note
TS15: migrating neural crest Present 8F AaBb
Specimen 8F -/-;-/-: embryonic day 9.5; Hoxa1tm1Mrc/Hoxa1tm1Mrc, Hoxb1tm3Mrc/Hoxb1tm3Mrc (more )
Note: 20-25 somites. Double labeled: green - Crabp1; red - TUNEL.
Structure Level Pattern Image Note
TS15: migrating neural crest Present 8F aabb
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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