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Gene Expression Data
Assay Details
Assay
Reference: J:41540 Rossel M, et al., Mice mutant for both Hoxa1 and Hoxb1 show extensive remodeling of the hindbrain and defects in craniofacial development. Development. 1999 Nov;126(22):5027-40
Assay type: RNA in situ
MGI Accession ID: MGI:1346696
Gene symbol: Pax1
Gene name: paired box 1
Probe: Pax1 probe6
Probe preparation: RNA
Results
Specimen 2L: embryonic day 10.5; Hoxa1tm1Mrc/Hoxa1+, Hoxb1tm3Mrc/Hoxb1+ (more )
Structure Level Pattern Image Note
TS17: 1st branchial pouch endoderm Present 2L
TS17: 2nd branchial pouch endoderm Present 2L
TS17: 3rd branchial pouch endoderm Present 2L
Specimen 2M: embryonic day 10.5; Hoxa1tm1Mrc/Hoxa1tm1Mrc (more )
Structure Level Pattern Image Note
TS17: 1st branchial pouch endoderm Present 2M Expression in this mutant is similar to wild-type in this tissue.
TS17: 2nd branchial pouch endoderm Present 2M Expression in this mutant is similar to wild-type in this tissue.
TS17: 3rd branchial pouch endoderm Present 2M Expression in this mutant is similar to wild-type in this tissue.
Specimen 2N: embryonic day 10.5; Hoxa1tm1Mrc/Hoxa1tm1Mrc, Hoxb1tm3Mrc/Hoxb1+ (more )
Note: There is a slight shift in position of the 2nd and 3rd branchial pouches towards the 1st branchial pouch in this mutant.
Structure Level Pattern Image Note
TS17: 2nd branchial pouch endoderm Present 2N There is a slight shift in the position of the 2nd and 3rd branchial pouches towards the 1st branchial pouch in this mutant.
TS17: 3rd branchial pouch endoderm Present 2N There is a slight shift in the position of the 2nd and 3rd branchial pouches towards the 1st branchial pouch in this mutant.
TS17: 1st branchial pouch endoderm Present 2N
Specimen 20: embryonic day 10.5; Hoxa1tm1Mrc/Hoxa1tm1Mrc, Hoxb1tm3Mrc/Hoxb1tm3Mrc (more )
Note: The 2nd branchial pouch is missing in this mutant and the shape of the 3rd branchial pouch is distorted relative to controls.
Structure Level Pattern Image Note
TS17: 1st branchial pouch endoderm Present 2O
TS17: 3rd branchial pouch endoderm Present 2O
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory