Gene Expression Data
Assay Details
Assay
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Reference:
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J:54640
Pearce JJ, et al., A mouse cerberus/Dan-related gene family. Dev Biol. 1999 May 1;209(1):98-110
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:1345394
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Gene symbol:
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Grem1
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Gene name:
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gremlin 1, DAN family BMP antagonist
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Probe:
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Drm probe1
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Results
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Specimen
6A:
embryonic day 8.5
(more )
Specimen
6A:
(close )
Genetic Background:
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Not Specified
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Age:
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embryonic day 8.5
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Sex:
|
Not Specified
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Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS13: trunk unsegmented mesenchyme |
Present |
Regionally restricted |
6A
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Expression was confined to a stripe of mesoderm at the lateral edge of the presomitic mesoderm.
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TS13: head somite |
Present |
Regionally restricted |
6A
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More anteriorly, expression was found in the lateral-most aspects of the developing somites.
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TS13: trunk somite |
Present |
Regionally restricted |
6A
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More anteriorly, expression was found in the lateral-most aspects of the developing somites.
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Specimen
6B:
embryonic day 8.5
(more )
Specimen
6B:
(close )
Genetic Background:
|
Not Specified
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Age:
|
embryonic day 8.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS13: future prosencephalon |
Present |
Regionally restricted |
6B
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Expression was seen in the anterior ventral forebrain.
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Specimen
6C:
embryonic day 9.5
(more )
Specimen
6C:
(close )
Genetic Background:
|
Not Specified
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Age:
|
embryonic day 9.5
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Sex:
|
Not Specified
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Type:
|
whole mount
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Specimen
6D:
embryonic day 10.5
(more )
Specimen
6D:
(close )
Genetic Background:
|
Not Specified
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Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS17: trunk dermomyotome |
Present |
Regionally restricted |
6D
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Expression was restricted to the medial and lateral extremes of the dermamyotome, with prominent expression seen in the epithelial balls of the lateral myotome and overlying dermis of the interlimb region.
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TS17: limb |
Present |
Regionally restricted |
6D
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Expression becomes restricted to a dorsal proximal domain.
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Specimen
6E:
embryonic day 9.5
(more )
Specimen
6E:
(close )
Genetic Background:
|
Not Specified
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Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
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Type:
|
whole mount
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Specimen
6F:
embryonic day 8.5
(more )
Specimen
6F:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 8.5
|
Sex:
|
Not Specified
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Type:
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section
|
Structure |
Level |
Pattern |
Image |
Note |
TS13: trunk unsegmented mesenchyme |
Present |
Regionally restricted |
6F
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Expression was confined to a stripe of mesoderm at the lateral edge of the presomitic mesoderm.
|
Specimen
6G:
embryonic day 9.5
(more )
Specimen
6G:
(close )
Genetic Background:
|
Not Specified
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Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
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Type:
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section
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Structure |
Level |
Pattern |
Image |
Note |
TS15: trunk somite |
Present |
Regionally restricted |
6G
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Expression was seen in the lateral-most aspects of developing somites.
|
TS15: trunk dermomyotome |
Present |
Regionally restricted |
6G
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An additional domain of expression was seen in the medial aspects of the dermamyotome of maturing anterior somites.
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TS15: forelimb bud mesenchyme |
Present |
Regionally restricted |
6G
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Expression was observed in the dorsal and ventral mesenchyme of the emergent limb buds.
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Specimen
6H:
embryonic day 9.5
(more )
Specimen
6H:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 9.5
|
Sex:
|
Not Specified
|
Type:
|
whole mount
|
Structure |
Level |
Pattern |
Image |
Note |
TS15: future hindbrain |
Present |
Regionally restricted |
6H
|
Expression was restricted to the roof plate at the midbrain-hindbrain junction area.
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TS15: future midbrain roof plate |
Present |
Regionally restricted |
6H
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Expression was restricted to the roof plate at the midbrain-hindbrain junction area.
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Specimen
not shown:
embryonic day 10.5
(more )
Specimen
not shown:
(close )
Genetic Background:
|
Not Specified
|
Age:
|
embryonic day 10.5
|
Sex:
|
Not Specified
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Type:
|
whole mount
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Specimen
6I:
embryonic day 11.5
(more )
Specimen
6I:
(close )
Genetic Background:
|
Not Specified
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Age:
|
embryonic day 11.5
|
Sex:
|
Not Specified
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Type:
|
whole mount
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Specimen
6J:
embryonic day 11.5
(more )
Specimen
6J:
(close )
Genetic Background:
|
Not Specified
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Age:
|
embryonic day 11.5
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Sex:
|
Not Specified
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Type:
|
whole mount
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Structure |
Level |
Pattern |
Image |
Note |
TS19: limb |
Present |
Regionally restricted |
6J
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Expression becomes restricted to the proximal interdigital regions.
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