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Gene Expression Data
Assay Details
Assay
Reference: J:31477 Favier B, et al., Functional cooperation between the non-paralogous genes Hoxa-10 and Hoxd-11 in the developing forelimb and axial skeleton. Development. 1996 Feb;122(2):449-60
Assay type: RNA in situ
MGI Accession ID: MGI:1344047
Gene symbol: Hoxa10
Gene name: homeobox A10
Probe: pbH1.8-320E-S
Probe preparation: RNA
Results
Specimen 13.5 dpc: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: limb Present Graded 1a Hoxa-10 Transcripts were preferentially expressed around the differentiating skeletal elements of the proximal segments of the limbs. Transcripts were much more diffuse in distal regions and decreased toward the footplates.
TS21: femur cartilage condensation Strong 1a Hoxa-10
TS21: humerus cartilage condensation Strong 1a Hoxa-10
TS21: radius-ulna cartilage condensation Moderate 1d Hoxa-10 Transcripts had a more diffuse distribution than Hoxd11 transcripts.

Specimen 14.5 dpc: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: femur cartilage condensation Present Graded 1b Hoxa-10 Expression was detected around the femur primordium, with higher transcript levels toward its proximal extremity in the area of the presumptive trochanter, and around its distal extremity.
TS22: knee mesenchyme Present 1b Hoxa-10 Hoxa10 transcripts were more widely distributed than Hoxd10 transcripts in the mesenchyme of the developing knee region.
TS22: forelimb Present Graded 1b Hoxa-10 Expression patterns in the developing forelimb, similar to those in the hindlimb, were observed at 14.5 dpc.

Specimen 12.5 dpc: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: hand Weak 1c Hoxa-10
TS20: radius-ulna pre-cartilage condensation Moderate 1c Hoxa-10 Hoxa10 transcripts were more diffusely distributed than Hoxd11 transcripts.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory