Pax1 RNase protection Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:16332 Koseki H, et al., A role for Pax-1 as a mediator of notochordal signals during the dorsoventral specification of vertebrae. Development. 1993 Nov;119(3):649-60
Assay type:	RNase protection
MGI Accession ID:	MGI:1343406
Gene symbol:	Pax1
Gene name:	paired box 1

Probe:	Pax1 probe3
Probe preparation:	Antisense RNA
Visualized with:	Autoradiography

Results

	Sample Information		Bands	Other Sample Information
Lane	Age	Structure	Size Not Specified	Amount	Genetic Background	Mutant Allele(s)	Sex
+/+	E10.5	TS17: embryo	Present	Not Specified	Not Specified		Not Specified
Sd	E10.5	TS17: embryo	Present (a)	Not Specified	involves: C57BL/6 * C57BL/6ByJ	Etn2^Sd/Etn2^Sd	Not Specified
+/+	E13.5	TS21: embryo	Present	Not Specified	Not Specified		Not Specified
Sd	E13.5	TS21: embryo	Weak (b)	Not Specified	involves: C57BL/6 * C57BL/6ByJ	Etn2^Sd/Etn2^Sd	Not Specified
+/Sd	E13.5	TS21: embryo	Present	Not Specified	involves: C57BL/6 * C57BL/6ByJ	Etn2^Sd/Etn2⁺	Not Specified
+/Un	E13.5	TS21: embryo	Present	Not Specified	involves: C57BL/6 * CC57BR/MvY	Pax1^Un-s/Pax1⁺	Not Specified
+/Sd +/Un	E13.5	TS21: embryo	Weak (c)	Not Specified	involves: C57BL/6 * C57BL/6ByJ * CC57BR/MvY	Pax1^Un-s/Pax1⁺, Etn2^Sd/Etn2⁺	Not Specified

Notes:
(a) No significant difference was seen compared to wild-type.
(b) Expression was reduced to 40% of the wild-type level.
(c) The compound heterozygote expresses less than either of the single heterozygotes.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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