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Gene Expression Data
Assay Details
Assay
Reference: J:29564 Dolle P, et al., Retinoic acid receptors and cellular retinoid binding proteins. I. A systematic study of their differential pattern of transcription during mouse organogenesis. Development. 1990 Dec;110(4):1133-51
Assay type: RNA in situ
MGI Accession ID: MGI:1342268
Gene symbol: Crabp1
Gene name: cellular retinoic acid binding protein I
Probe: Crabp-1 cDNA1
Probe preparation: Antisense labelled with S35 RNA
Visualized with: Autoradiography
Results
Specimen 1: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: embryo Present Regionally restricted 1_CRABP
TS20: fronto-nasal process mesenchyme Strong Regionally restricted 1_CRABP Transcripts were most abundant in superficial frontonasal mesenchyme and absent in central regions.
TS20: tongue Present Regionally restricted 1_CRABP Transcripts were preferentially expressed in the distal half of the tongue.
TS20: mandibular process Present Regionally restricted 1_CRABP Transcripts exhibited a complex distribution in the mandible.
TS20: stomach mesenchyme Present Regionally restricted 1_CRABP Transcripts were detected only in discrete dorsally located regions of the stomach mesenchyme which are close to the dorsal mesentery.
TS20: cardiovascular system Present Regionally restricted 1_CRABP Transcripts were strongly expressed in the tissue adjacent to the endocardial cushions and in the walls of large arterial trunks; then were absent from the walls of the vascular trunks in the vicinity of the heart.

Specimen 2A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: 1st branchial arch mandibular component mesenchyme Strong Regionally restricted 2A CRABP Transcripts were most abundant in the rostral part of the frontonasal mesenchyme and in the distal part of the mandibular arch mesenchyme.
TS17: fronto-nasal process mesenchyme Strong Regionally restricted 2A CRABP Transcripts were most abundant in the rostral part of the frontonasal mesenchyme and in the distal part of the mandibular arch mesenchyme.
TS17: 1st branchial arch maxillary component Trace 2A CRABP
TS17: eye Weak Regionally restricted 2A CRABP Weak expression could be seen in the neural retina.

Specimen 2B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: fronto-nasal process mesenchyme Strong Regionally restricted 2B CRABP Transcripts were most abundant in superficial frontonasal mesenchyme and absent in central regions.
TS20: tongue Present Regionally restricted 2B CRABP Transcripts were preferentially expressed in the distal half of the tongue.
TS20: mandibular process Present Regionally restricted 2B CRABP Transcripts exhibited a complex distribution in the mandible.

Specimen 3: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: molar mesenchyme Present Regionally restricted 3_CRABP Transcripts were found in the deeper regions of the dental sac and in cells close to the jaw cartilage.

Specimen 4A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: embryo Present Regionally restricted 4A CRABP Expression was detected in cells located between the trachea and the heart.
TS20: trachea Absent 4A CRABP
TS20: cardiovascular system Present Regionally restricted 4A CRABP Transcripts were strongly expressed in the tissue adjacent to the endocardial cushions and in the walls of large arterial trunks; then were absent from the walls of the vascular trunks in the vicinity of the heart.

Specimen not shown: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lung Absent

Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: heart Absent
TS22: lung Absent

Specimen 4C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: stomach mesenchyme Present Regionally restricted 4C CRABP Transcripts were detected only in discrete dorsally located regions of the stomach mesenchyme which are close to the dorsal mesentery.
TS20: liver Absent 4C CRABP
TS20: intraembryonic coelom Absent 4C CRABP No significant labelling was found in the diaphragm.
TS20: pancreas Absent 4C CRABP

Specimen 5A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: gut dorsal mesentery Present 5A CRABP
TS17: trunk mesenchyme Present Regionally restricted 5A CRABP Transcripts were restricted to the mesenchyme in the vicinity of the aorta and posterior cardinal veins.

Specimen 5B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: metanephros Present Regionally restricted 5B CRABP Labelling was restricted to the cortical (nephrogenic) mesenchymal cells and to the metanephric capsule.
TS22: adrenal gland Absent 5B CRABP

Specimen 6A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: genital tubercle Present Regionally restricted 6A CRABP Transcripts were restricted to the distal mesenchyme.

Specimen 7A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: eye Present Regionally restricted 7A CRABP Transcripts were seen in the central area of the neural retina and in the innermost layer of the prechoroidal mesenchyme.
TS20: neural retinal epithelium Present Regionally restricted 7A CRABP Transcripts were seen in the central area of the neural retina and in the innermost layer of the prechoroidal mesenchyme.

Specimen 7B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: head Present Regionally restricted 7B CRABP Transcripts were generally, but not always, found in areas surrounding cartilaginous elements.
TS22: inner ear mesenchyme Strong 7B CRABP
TS22: inner ear epithelium Present Regionally restricted 7B CRABP Expression is present in most of the mesenchyme.

Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cochlear duct epithelium Present Regionally restricted Expression was in a very limited area of the cochlea epithelium.

Specimen not shown: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: nasal pit Absent Transcripts were undetectable in the ectodermal component of the olfactory pits.
TS17: Rathke's pouch Absent
TS17: head mesenchyme Strong Regionally restricted Labelling was particularly intense in the mesenchyme closely surrounding the olfactory pits.

Specimen 7C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: embryo Present Regionally restricted 7C CRABP Transcripts were generally, but not always, found in areas surrounding cartilaginous elements.
TS21: nasal cavity Strong Regionally restricted 7C CRABP Transcripts were abundant in the respiratory mesenchyme, but were absent in the olfactory mesenchyme.
TS21: olfactory epithelium Strong 7C CRABP
TS21: nasal cavity respiratory epithelium Absent 7C CRABP

Specimen 8A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: olfactory epithelium Strong Regionally restricted 8A CRABP

Specimen 8B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: dermis Strong Regionally restricted 8B CRABP Strong labelling was detected in dermal cells that lie in the close vicinity of the developing whisker follicles.
TS22: epidermis Absent 8B CRABP

Specimen 9: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: hindlimb Present 9_CRABP

Specimen 10A: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: pituitary gland Present Regionally restricted 10A CRABP Transcripts were detected only in some surrounding mesenchymal cells.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory