Gene Expression Data
Assay Details
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Assay
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Reference:
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J:56426
Bi W, et al., The transcription factor MEF2C-null mouse exhibits complex vascular malformations and reduced cardiac expression of angiopoietin 1 and VEGF. Dev Biol. 1999 Jul 15;211(2):255-67
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:1342002
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Gene symbol:
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Pecam1
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Gene name:
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platelet/endothelial cell adhesion molecule 1
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Antibody:
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MEC 13.3
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Detection system:
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Secondary antibody
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Results
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Specimen
1A:
embryonic day 9.5
(more  )
Specimen
1A:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
1B:
embryonic day 9.5
(more )
Specimen
1B:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
1C:
embryonic day 9.5
(more )
Specimen
1C:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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Specimen
1D:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd
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Mutant Allele(s):
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Mef2ctm1Eno/Mef2ctm1Eno
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: blood vessel |
Present |
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1D
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Expression was detected in the mutant embryos as in wild type, but the head vessels were dilated in the mutant and had less complex branching in comparison with the wild type.
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Specimen
1E:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd
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Mutant Allele(s):
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Mef2ctm1Eno/Mef2ctm1Eno
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: dorsal aorta |
Present |
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1E
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Expression was detected in the dorsal aorta as in wild type, but the dorsal aorta caudal to the heart is enlarged and dilated, and dorsal to the heart is much small and irregularly shaped in the mutant compared to wild type.
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Specimen
1F:
(close )
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Genetic Background:
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involves: 129S7/SvEvBrd
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Mutant Allele(s):
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Mef2ctm1Eno/Mef2ctm1Eno
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Age:
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embryonic day 9.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS15: dorsal aorta |
Present |
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1F
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Expression was detected in the dorsal aorta as in wild type, but the dorsal aorta caudal to the heart is enlarged and dilated, and dorsal to the heart is much small and irregularly shaped in the mutant compared to wild type.
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| TS15: arterial system |
Present |
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1F
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Expression was detected in the intersegmental arteries as in wild type, but the vessels caudal to the heart are enlarged and dilated.
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