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Gene Expression Data
Assay Details
Assay
Reference: J:50462 Dassule HR, et al., Analysis of epithelial-mesenchymal interactions in the initial morphogenesis of the mammalian tooth. Dev Biol. 1998 Oct 15;202(2):215-27
Assay type: RNA in situ
MGI Accession ID: MGI:1340546
Gene symbol: Gli1
Gene name: GLI-Kruppel family member GLI1
Probe: Gli cDNA3
Probe preparation: RNA
Results
Specimen 1F: embryonic day 11.0 (more )
Structure Level Pattern Image Note
TS18: 1st branchial arch mandibular component mesenchyme Strong Regionally restricted 1F Gli is strongly expressed in the mesenchyme along the mesial-distal axis in a pattern that is complimentary to and somewhat broader than Shh.
TS18: tongue Present 1F
Specimen 1L: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: mandible primordium Present Regionally restricted 1L Gli is strongly expressed in the mesenchyme along the mesial-distal axis in a pattern that is complimentary to and somewhat broader than Shh. Gli is also detected in the epithelium.
TS19: tongue Present 1L
Specimen 1R: embryonic day 12.0 (more )
Structure Level Pattern Image Note
TS20: mandible primordium Weak Regionally restricted 1R Gli expression is maintained at low levels in the diastema.
TS20: tongue Present 1R
Specimen 1X: embryonic day 12.0 (more )
Note: Tissue was embedded in 30% BSA, 0.49% gelatin, 20% sucrose in PBS and crosslinked with glutaraldehyde.
Structure Level Pattern Image Note
TS20: mandible primordium Present Regionally restricted 1X Gli transcripts are detected in both the mesenchyme and at lower levels in the incisor epithelium.
Specimen 1AA: embryonic day 12.5 (more )
Note: Tissue was embedded in 30% BSA, 0.49% gelatin, 20% sucrose in PBS and crosslinked with glutaraldehyde.
Structure Level Pattern Image Note
TS20: tongue Present Regionally restricted 1AA Gli expression is restricted to the mesenchyme. Gli is more broadly expressed in than Ptc.
TS20: mandible primordium Present 1AA
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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