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Gene Expression Data
Assay Details
Assay
Reference: J:56093 Bruneau BG, et al., Chamber-specific cardiac expression of Tbx5 and heart defects in Holt-Oram syndrome. Dev Biol. 1999 Jul 1;211(1):100-8
Assay type: RNA in situ
MGI Accession ID: MGI:1340496
Gene symbol: Tbx5
Gene name: T-box 5
Probe: Tbx5 probe2
Probe preparation: Antisense labelled with P33 RNA
Visualized with: Autoradiography
Results
Specimen 4A: embryonic day 13.5 (more )
Note: Transverse section showing four-chambered view of the heart.
Structure Level Pattern Image Note
TS21: inferior vena cava Present 4A
TS21: left superior vena cava Present 4A
TS21: right superior vena cava Present 4A
TS21: heart atrium Strong 4A
TS21: heart right ventricle Present Regionally restricted 4A Expression is limited to the trabeculae.
TS21: heart left ventricle Present Regionally restricted 4A Expression is higher in the trabeculae than in the ventricular free wall.
TS21: interventricular septum Present Regionally restricted 4A Expression is limited to the left aspect of the septum.
Specimen 4B: embryonic day 13.5 (more )
Note: Close up of a posterior section of the heart.
Structure Level Pattern Image Note
TS21: interatrial septum Present 4B
TS21: heart valve Present Regionally restricted 4B Expression is in the atrioventricular valves with higher expression on the atrial side of the valve leaflets.
TS21: inferior vena cava Present 4B
TS21: left superior vena cava Present 4B
TS21: right superior vena cava Present 4B
Specimen 4C: embryonic day 13.5 (more )
Note: A section more posterior to that shown in (B).
Structure Level Pattern Image Note
TS21: heart atrium Present 4C
TS21: left superior vena cava Present 4C
TS21: right superior vena cava Present 4C
TS21: heart left ventricle Present Regionally restricted 4C Expression levels in the trabeculae are higher than in the ventricular free wall.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/14/2024
MGI 6.23 		The Jackson Laboratory