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Gene Expression Data
Assay Details
Assay
Reference: J:24368 Leonard L, et al., Anteriorization of CRABP-I expression by retinoic acid in the developing mouse central nervous system and its relationship to teratogenesis. Dev Biol. 1995 Apr;168(2):514-28
Assay type: RNA in situ
MGI Accession ID: MGI:1340377
Gene symbol: Crabp1
Gene name: cellular retinoic acid binding protein I
Probe: Crabp1 probe2
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1A: embryonic day 8.0 (more )
Note: Late head fold/early somite stage embryo.
Structure Level Pattern Image Note
TS12: neural ectoderm Present Regionally restricted 1A Expression is in the neuroepithelium caudal to the preotic sulcus. Based on comparison to Egr2 expression, Crabp1 is expressed in future rhombomere 4.

Specimen 1C: embryonic day 8.5 (more )
Note: 6/7 somite stage.
Structure Level Pattern Image Note
TS13: future hindbrain Present Regionally restricted 1C Expression is in a wide stripe adjacent to the preotic sulcus.

Specimen 1E: embryonic day 8.5 (more )
Note: 6/7 somite stage.
Structure Level Pattern Image Note
TS13: future hindbrain Present Graded 1E Expression is throughout the full thickness of the neuroepithelium. There are higher levels of expression in the dorsal half than in the ventral half.
TS13: rhombomere 5 neural crest Present 1E

Specimen 2A: embryonic day 9.5 (more )
Note: 15-20 somite stage.
Structure Level Pattern Image Note
TS15: rhombomere 2 Weak 2A
TS15: rhombomere 4 Strong 2A
TS15: rhombomere 5 Strong 2A
TS15: rhombomere 6 Strong 2A
TS15: branchial arch mesenchyme derived from neural crest Present 2A
TS15: future spinal cord Present Regionally restricted 2A Expression is in the mesenchyme derived from the neural crest.
TS15: future midbrain Present Regionally restricted 2A Expression is in the mesencephalic trigeminal neurons.

Specimen 2B: embryonic day 9.5 (more )
Note: 15-20 somite stage.
Structure Level Pattern Image Note
TS15: neural tube lateral wall Present Regionally restricted 2B Expression is in the mantle layer in is a unique set of commisural neurons.

Specimen 2C: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: hindbrain Present Regionally restricted 2C Expression is in the mesencephalic neurons of the trigeminal nerve. Expression extneds down the nerve to rhombomere 2 in the hindbrain.
TS17: midbrain Present Regionally restricted 2C Expression is in the mesencephalic neurons of the trigeminal nerve. Expression extneds down the nerve to rhombomere 2 in the hindbrain.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory