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Gene Expression Data
Assay Details
Assay
Reference: J:55577 Wehrle-Haller B, et al., Altered cell-surface targeting of stem cell factor causes loss of melanocyte precursors in Steel17H mutant mice. Dev Biol. 1999 Jun 1;210(1):71-86
Assay type: RNA in situ
MGI Accession ID: MGI:1339361
Gene symbol: Dct
Gene name: dopachrome tautomerase
Probe: TRP-2 probe4
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2A: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: tail mesenchyme derived from neural crest Present Regionally restricted 2A Expression is in the migration staging area (MSA) and disbursed on the lateral neural crest migration pathway at the hindlimb level.
TS19: trunk mesenchyme derived from neural crest Present Regionally restricted 2A Expression is in the migration staging area (MSA) and disbursed on the lateral neural crest migration pathway at the hindlimb level.

Specimen 2B: embryonic day 11.5; KitlSl-17H/KitlSl-17H (more )
Structure Level Pattern Image Note
TS19: tail mesenchyme derived from neural crest Present Regionally restricted 2B Expression is in the migration staging area (MSA) and disbursed on the lateral neural crest migration pathway at the hindlimb level. In mutant embryos, fewer cells stain than in the wild-type embryo.
TS19: trunk mesenchyme derived from neural crest Present Regionally restricted 2B Expression is in the migration staging area (MSA) and disbursed on the lateral neural crest migration pathway at the hindlimb level. In mutant embryos, fewer cells stain than in the wild-type embryo.

Specimen 2E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: outer ear Present Regionally restricted 2E Expression is in the ear pinna.

Specimen 2F: embryonic day 11.5; KitlSl-17H/KitlSl-17H (more )
Structure Level Pattern Image Note
TS19: outer ear Present Regionally restricted 2F In mutants, far fewer cells are labelled in the ear pinna than in wild-type embryos.

Specimen 2G: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: tail mesenchyme derived from neural crest Present Regionally restricted 2G Expression is in cells along the lateral migration pathway near the hindlimb.

Specimen 2H: embryonic day 12.5; KitlSl-17H/KitlSl-17H (more )
Structure Level Pattern Image Note
TS20: tail mesenchyme derived from neural crest Present Regionally restricted 2H Expression is in cells along the lateral migration pathway near the hindlimb. Fewer cells labelled in the mutant than in wild-type embryos.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory