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Gene Expression Data
Assay Details
Assay
Reference: J:41809 Filosa S, et al., goosecoid and HNF-3 beta genetically interact to regulate neural tube patterning during mouse embryogenesis. Development. 1997 JUL;124(14):2843-2854
Assay type: Immunohistochemistry
MGI Accession ID: MGI:1338655
Gene symbol: Foxa2
Gene name: forkhead box A2
Antibody: anti-HNF3b
Results
Specimen 7.A: embryonic day 8.5; Foxa2tm1Jrt/Foxa2+, Gsctm1Bhr/Gsc+ (more )
Structure Level Pattern Image Note
TS13: embryo Present Regionally restricted 7A
Specimen 7.B: embryonic day 8.5; Foxa2tm1Jrt/Foxa2+, Gsctm1Bhr/Gsc+ (more )
Note: Embryos were embedded in 7.5% gelatin.
Structure Level Pattern Image Note
TS13: gut Present 7B
TS13: neural tube Present Regionally restricted 7B Expression is present in the ventral neural tube.
TS13: embryo mesenchyme Present Regionally restricted 7B Expression is present in the prechordal mesoderm.
Specimen 7.C: embryonic day 8.5; Foxa2tm1Jrt/Foxa2+, Gsctm1Bhr/Gsc+ (more )
Note: Embryos were embedded in 7.5% gelatin.
Structure Level Pattern Image Note
TS13: notochord Present 7C
TS13: neural tube Present Regionally restricted 7C Expression is present in the ventral neural tube.
Specimen 7.D: embryonic day 8.5; Foxa2tm1Jrt/Foxa2+, Gsctm1Bhr/Gsctm1Bhr (more )
Structure Level Pattern Image Note
TS13: embryo Present Regionally restricted 7D Expression was normal compared to double heterozygote.
Specimen 7.E: embryonic day 8.5; Foxa2tm1Jrt/Foxa2+, Gsctm1Bhr/Gsctm1Bhr (more )
Note: Embryos were embedded in 7.5% gelatin.
Structure Level Pattern Image Note
TS13: gut Present 7E
TS13: neural tube Present Regionally restricted 7E Expression was present in the ventral neural tube.
TS13: embryo mesenchyme Present Regionally restricted 7E Expression was present in the prechordal mesoderm.
Specimen 7.F: embryonic day 8.5; Foxa2tm1Jrt/Foxa2+, Gsctm1Bhr/Gsctm1Bhr (more )
Note: Embryos were embedded in 7.5% gelatin.
Structure Level Pattern Image Note
TS13: notochord Present 7F
TS13: neural tube Present Regionally restricted 7F Expression is present in the ventral neural cord.
Specimen 7.G: embryonic day 8.75; Foxa2tm1Jrt/Foxa2+, Gsctm1Bhr/Gsc+ (more )
Structure Level Pattern Image Note
TS13: embryo Present Regionally restricted 7G
Specimen 7.H: embryonic day 8.75; Foxa2tm1Jrt/Foxa2+, Gsctm1Bhr/Gsc+ (more )
Note: Embryos were embedded in 7.5% gelatin.
Structure Level Pattern Image Note
TS13: gut Present 7H
TS13: neural tube floor plate Present 7H
TS13: notochord Present 7H
TS13: oral region Present Regionally restricted 7H Expression is present in the oral epithelium.
TS13: paraxial mesenchyme Present Regionally restricted 7H Expression is present in the axial mesoderm.
Specimen 7.I: embryonic day 8.75; Foxa2tm1Jrt/Foxa2+, Gsctm1Bhr/Gsc+ (more )
Note: Embryos were embedded in 7.5% gelatin.
Structure Level Pattern Image Note
TS13: neural tube floor plate Present 7I
TS13: notochord Present 7I
Specimen 7.J: embryonic day 8.75; Foxa2tm1Jrt/Foxa2+, Gsctm1Bhr/Gsc+ (more )
Note: Embryos were embedded in 7.5% gelatin.
Structure Level Pattern Image Note
TS13: neural tube floor plate Present 7J
TS13: notochord Present 7J
Specimen 7.K: embryonic day 8.75; Foxa2tm1Jrt/Foxa2+, Gsctm1Bhr/Gsctm1Bhr (more )
Structure Level Pattern Image Note
TS13: embryo Present Regionally restricted 7K Expression is reduced in the double mutant.
Specimen 7.L: embryonic day 8.75; Foxa2tm1Jrt/Foxa2+, Gsctm1Bhr/Gsctm1Bhr (more )
Note: Embryos were embedded in 7.5% gelatin.
Structure Level Pattern Image Note
TS13: oral region Absent 7L Expression is lost in the oral epithelium of the double mutant embryo.
TS13: neural tube floor plate Present Regionally restricted 7L Expression is lost in the anterior part of the double mutant embryo, although it is present in the posterior.
TS13: gut Present 7L The size, shape, and position of the gut is abnormal.
TS13: paraxial mesenchyme Absent 7L There is no expression in the anterior axial mesoderm.
Specimen 7.M: embryonic day 8.75; Foxa2tm1Jrt/Foxa2+, Gsctm1Bhr/Gsctm1Bhr (more )
Note: Embryos were embedded in 7.5% gelatin.
Structure Level Pattern Image Note
TS13: gut Present 7M The size, shape, and position of the gut is abnormal.
Specimen 7.N: embryonic day 8.75; Foxa2tm1Jrt/Foxa2+, Gsctm1Bhr/Gsctm1Bhr (more )
Note: Embryos were embedded in 7.5% gelatin.
Structure Level Pattern Image Note
TS13: neural tube floor plate Present Regionally restricted 7N Expression is maintained in the posterior part of the double mutant embryo. It is missing in the anterior part of the embryo.
TS13: notochord Present Regionally restricted 7N Expression is maintained in the posterior part of the double mutant embryo. The notochord is missing in the anterior part of the embryo.
TS13: gut Present 7N The size, shape, and position of the gut is abnormal.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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